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(2R)-1-{4-[(4-Anilino-5-bromo-2-pyrimidinyl)amino]phenoxy}-3-(dimethylamino)-2-propanol
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
This compound is an experimental small molecule inhibitor targeting cyclin-dependent kinase 2 (CDK2), a serine/threonine-protein kinase involved in cell cycle regulation. CDK2 plays a critical role in the control of the cell cycle and is essential for meiosis. The drug acts by binding to and inhibiting CDK2, thereby potentially interfering with cellular proliferation processes relevant to cancer and other proliferative diseases. It has not been approved for clinical use and remains at the experimental stage[1][8].
- Other names
- (2R)-1-(4-((4-Anilino-5-bromo-2-pyrimidinyl)amino)phenoxy)-3-(dimethylamino)-2-propanol(2R)-1-(4-{[5-bromo-6-(phenylimino)-1,6-dihydropyrimidin-2-yl]amino}phenoxy)-3-(dimethylamino)propan-2-ol(2R)-1-{4-[ (4-anilino - 5-bromopyrimidin - 2 - yl ) amino ] phenoxy } - 3 -( dimethylamino ) propan - 2 - ol
02
Targets
CDK2 (Cyclin-dependent kinase 2)CDK1 (Cyclin-dependent kinase 1)
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